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In cardiovascular outcomes trials, GLP-1 receptor agonists reduced albuminuria and slowed eGFR decline, even when used with other potentially protective therapies in populations with T2D or obesity and relatively low CKD risk

doi: 10.1016/j.drudis.2016.01.013 12 AugestadI

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Resources: Pillar 2: Weight management (fat loss where appropriate) Where excess body fat (especially visceral and ectopic fat) is present, fat loss can materially improve insulin sensitivity

Another phase 2b study in patients with NASH with cirrhosis and severe portal hypertension is assessing the efficacy of three doses Emricasan (10, 50, 100 mg/day) on portal hypertension (ENCORE-PH, NCT02960204)

Someone managing other medications that affect digestive function may require a more tailored schedule